Chemotherapy induces secretion of exosomes loaded with heparanase that degrades extracellular matrix and impacts tumor and host cell behavior.
作者:
主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞系, 肿瘤(Cell Line, Tumor);抗药性, 肿瘤(Drug Resistance, Neoplasm);药物疗法(Drug Therapy);外泌体(Exosomes);细胞外基质(Extracellular Matrix);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);葡糖醛酸糖苷酶(Glucuronidase);人类(Humans);美法仑(Melphalan);小鼠(Mice);多发性骨髓瘤(Multiple Myeloma);寡肽类(Oligopeptides);信号传导(Signal Transduction);增量调节(Up-Regulation)
DOI
10.1016/j.matbio.2017.09.001
PMID
28888912
发布时间
2021-12-01
- 浏览8
Matrix biology
104-118页
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