Positive feedback of the amphiregulin-EGFR-ERK pathway mediates PM2.5 from wood smoke-induced MUC5AC expression in epithelial cells.
作者:
主题词
动物(Animals);自身分泌性细胞间通讯(Autocrine Communication);上皮细胞(Epithelial Cells);细胞外信号调节MAP激酶类(Extracellular Signal-Regulated MAP Kinases);荧光抗体技术(Fluorescent Antibody Technique);基因表达调控(Gene Expression Regulation);杯状细胞(Goblet Cells);人类(Humans);配体(Ligands);黏蛋白5AC(Mucin 5AC);颗粒物(Particulate Matter);大鼠(Rats);呼吸道黏膜(Respiratory Mucosa);信号传导(Signal Transduction);烟(Smoke);转录, 遗传(Transcription, Genetic);木材(Wood)
DOI
10.1038/s41598-017-11541-1
PMID
28894207
发布时间
2019-06-13
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Scientific reports
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