Collective invasion in ductal and lobular breast cancer associates with distant metastasis.

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作者： Antoine A,Khalil ^[1] ; Olga,Ilina ^[2] ; Pavlo G,Gritsenko ^[2] ; Peter,Bult ^[3] ; Paul N,Span ^[4] ; Peter,Friedl ^[5]

作者单位： Department of Dermatology and Graduate School of Life Sciences, University of Würzburg, Würzburg, Germany. ^[1] Department of Cell Biology, Radboud University Medical Center, 6500 HB, Nijmegen, The Netherlands. ^[2] Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands. ^[3] Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, The Netherlands. ^[4] Department of Dermatology and Graduate School of Life Sciences, University of Würzburg, Würzburg, Germany. Peter.Friedl@radboudumc.nl. ^[5] Department of Cell Biology, Radboud University Medical Center, 6500 HB, Nijmegen, The Netherlands. Peter.Friedl@radboudumc.nl. ^[6] David H. Koch Center for Applied Genitourinary Cancers, The University of Texas MD Anderson Cancer Center, Houston, TX, 77070, USA. Peter.Friedl@radboudumc.nl. ^[7] Cancer Genomics Centre, 3584 CG, Utrecht, The Netherlands. Peter.Friedl@radboudumc.nl. ^[8]

关键词 Adipose tissue Breast cancer CD44 Cell–cell junctions Collective invasion Distant metastasis E-cadherin Epithelial-to-mesenchymal transition