换一批
换一批FGFR inhibitor, AZD4547, impedes the stemness of mammary epithelial cells in the premalignant tissues of MMTV-ErbB2 transgenic mice.
第一作者：
Qingxia,Zhao
第一单位：
Julius L. Chambers Biomedical/Biotechnology Research Institute, Department of Biological and Biomedical Sciences, North Carolina Central University, North Carolina Research Campus, Kannapolis, North Carolina, USA.
作者：
主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);苯甲酰胺类(Benzamides);细胞周期(Cell Cycle);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);细胞存活(Cell Survival);上皮细胞(Epithelial Cells);女(雌)性(Female);基因表达(Gene Expression);乳房肿瘤, 动物(Mammary Neoplasms, Animal);乳房肿瘤, 实验性(Mammary Neoplasms, Experimental);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);哌嗪类(Piperazines);癌前状态(Precancerous Conditions);吡唑类(Pyrazoles);受体, 成纤维细胞生长因子(Receptors, Fibroblast Growth Factor);信号传导(Signal Transduction);干细胞(Stem Cells)
DOI
10.1038/s41598-017-11751-7
PMID
28900173
发布时间
2019-06-21
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