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Past matrix stiffness primes epithelial cells and regulates their future collective migration through a mechanical memory.

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第一作者： Samila,Nasrollahi

第一单位： Department of Mechanical Engineering and Materials Science, Washington University, Saint Louis, MO 63130, USA.

作者： Samila,Nasrollahi ^[1] ; Christopher,Walter ^[2] ; Andrew J,Loza ^[3] ; Gregory V,Schimizzi ^[3] ; Gregory D,Longmore ^[4] ; Amit,Pathak ^[5]

作者单位： Department of Mechanical Engineering and Materials Science, Washington University, Saint Louis, MO 63130, USA. ^[1] Department of Biomedical Engineering, Washington University, Saint Louis, MO 63130, USA. ^[2] Department of Biochemistry and Biophysics, Washington University, St. Louis MO 63110, USA; ICCE Institute, Washington University, St. Louis MO 63110, USA. ^[3] Departments of Medicine, Cell Biology and Physiology, Washington University, St. Louis, MO 63110 USA; ICCE Institute, Washington University, St. Louis MO 63110, USA. ^[4] Department of Mechanical Engineering and Materials Science, Washington University, Saint Louis, MO 63130, USA; Department of Biomedical Engineering, Washington University, Saint Louis, MO 63130, USA. Electronic address: pathaka@wustl.edu. ^[5]

关键词 Collective cell migration Extracellular matrix Mechanical memory Mechanotransduction Stiffness

医学主题词细胞运动(Cell Movement);细胞骨架(Cytoskeleton);上皮细胞(Epithelial Cells);细胞外基质(Extracellular Matrix);焦点黏着(Focal Adhesions);人类(Humans);动力传导, 细胞(Mechanotransduction, Cellular)

DOI 10.1016/j.biomaterials.2017.09.012

PMID 28918264

发布时间 2018-11-13

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准确一般字义偏差语意偏离译文作用小提交