Thrombospondin-1 Gene Deficiency Worsens the Neurological Outcomes of Traumatic Brain Injury in Mice.

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第一作者： Chongjie,Cheng

第一单位： Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

作者： Chongjie,Cheng ^[1] ; Zhanyang,Yu ^[2] ; Song,Zhao ^[2] ; Zhengbu,Liao ^[3] ; Changhong,Xing ^[1] ; Yinghua,Jiang ^[2] ; Yong-Guang,Yang ^[2] ; Michael J,Whalen ^[1] ; Eng H,Lo ^[2] ; Xiaochuan,Sun ^[4] ; Xiaoying,Wang ^[5]

作者单位： Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. ^[1] Neuroprotection Research Laboratory, Departments of Neurology and Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA. ^[2] Departments of Orthopedic and Neurosurgery, The First Bethune Hospital of Jilin University, Changchun, Jilin, China. ^[3] Columbia Center for Translational Immunology, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA. ^[4] Department of Pediatrics, Pediatric Critical Care Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA. ^[5]

关键词 Thromspondin-1 (TSP-1)angiogenesis blood-brain-barrier morris water maze (MWM)neurological severity score (NSS)synaptogenesis.traumatic brain injury