换一批Amino-functionalized poloxamer 407 with both mucoadhesive and thermosensitive properties: preparation, characterization and application in a vaginal drug delivery system.
第一作者：
Liqian,Ci
第一单位：
School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China.
作者：
关键词
ACN, anhydrous acetonitrileAG, acetate gossypolAG-loaded FG, F127 gel-loaded with acetate gossypolAG-loaded NFG, F127-NH2 gel-loaded with acetate gossypolANOVA, one-way analysis of varianceAcetate gossypolAmino groupC6, 6-coumarinCDI, carbonyl diimidazoleCMC, critical micelle concentrationDAPI, 2-(4-amidinophenyl)-6-indolecarbamindine dihydrochlorideDLS, dynamic light scatteringDPH, 1,6-diphenyl-1,3,5-hexatrieneDTT, dithiothreitolDiR, 1,1?-dioctadecyl-3,3,3?,3?-tetramethylindotricarbocyanine iodideEDTA, ethylenediamine tetraacetic acidEMS, endometriosisF127, Pluronic F127FG, F127 gelFTIR, Fourier transform infraredH&E, hematoxylin and eosinICR, Institute of Cancer ResearchIn situ hydrogelMucoadhesive gelNF, amino-functionalised poloxamer 407NFG, aminated poloxamer 407-based temperature sensitive hydrogelNMR, nuclear magnetic resonanceOCT, optical coherence tomographyPBS, phosphate buffered salinePDI, polydispersity indexPEO, poly(ethylene oxide)PGM, porcine gastric mucinPPO, poly(propylene oxide)Poloxamer 407TEM, transmission electron microscopyVFS, vaginal fluid stimulant
DOI
10.1016/j.apsb.2017.03.002
PMID
28924553
发布时间
2023-09-18
- 浏览21
Acta pharmaceutica Sinica. B
2017年7卷5期
593-602页
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