Engineered cells for costimulatory enhancement combined with IL-21 enhance the generation of PD-1-disrupted CTLs for adoptive immunotherapy.
作者:
主题词
4-1BB配体(4-1BB Ligand);癌症疫苗(Cancer Vaccines);细胞增殖(Cell Proliferation);细胞毒性, 免疫(Cytotoxicity, Immunologic);遗传工程(Genetic Engineering);人类(Humans);免疫耐受(Immune Tolerance);免疫疗法, 过继(Immunotherapy, Adoptive);白细胞介素类(Interleukins);K562细胞(K562 Cells);淋巴细胞活化(Lymphocyte Activation);肿瘤(Neoplasms);T淋巴细胞, 细胞毒性(T-Lymphocytes, Cytotoxic)
DOI
10.1016/j.cellimm.2017.09.003
PMID
28935250
发布时间
2018-12-02
- 浏览6
Cellular immunology
38-45页
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