Trans-sialidase-based vaccine candidate protects against <i>Trypanosoma cruzi</i> infection, not only inducing an effector immune response but also affecting cells with regulatory/suppressor phenotype.

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作者： Estefanía,Prochetto ^[1] ; Carolina,Roldán ^[1] ; Iván A,Bontempi ^[1] ; Daiana,Bertona ^[2] ; Luz,Peverengo ^[1] ; Miguel H,Vicco ^[1] ; Luz M,Rodeles ^[2] ; Ana R,Pérez ^[2] ; Iván S,Marcipar ^[3] ; Gabriel,Cabrera ^[1]

作者单位： Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe, Argentina. ^[1] Facultad de Ciencias Médicas, Universidad Nacional del Litoral, Santa Fe, Argentina. ^[2] IDICER-CONICET and Instituto de Inmunología, Facultad de Ciencias Médicas, Universidad Nacional de Rosario, Santa Fe, Argentina. ^[3]

关键词 Immune response Immunity Immunology and Microbiology Section Trypanosoma cruzi foxp3 regulatory T cells myeloid-derived suppressor cells trans-sialidase vaccine

DOI 10.18632/oncotarget.18217

PMID 28938533

发布时间 2018-11-13

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准确一般字义偏差语意偏离译文作用小提交