Transfer of a Mouse Artificial Chromosome into Spermatogonial Stem Cells Generates Transchromosomic Mice.

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作者： Takashi,Shinohara ^[1] ; Kanako,Kazuki ^[2] ; Narumi,Ogonuki ^[3] ; Hiroko,Morimoto ^[1] ; Shogo,Matoba ^[3] ; Kei,Hiramatsu ^[4] ; Kazuhisa,Honma ^[4] ; Teruhiko,Suzuki ^[5] ; Takahiko,Hara ^[5] ; Atsuo,Ogura ^[3] ; Mitsuo,Oshimura ^[2] ; Mito,Kanatsu-Shinohara ^[6] ; Yasuhiro,Kazuki ^[7]

作者单位： Department of Molecular Genetics, Graduate School of Medicine, Kyoto University, Yoshida Konoe, Sakyo-ku, Kyoto 606-8501, Japan. ^[1] Chromosome Engineering Research Center (CERC), Tottori University, 86 Nishicho, Yonago 683-8503, Japan. ^[2] RIKEN BioResource Center, Tsukuba 305-0074, Japan. ^[3] Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University, Yonago 683-8503, Japan. ^[4] Stem Cell Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan. ^[5] Department of Molecular Genetics, Graduate School of Medicine, Kyoto University, Yoshida Konoe, Sakyo-ku, Kyoto 606-8501, Japan; Japan Science and Technology Agency, PRESTO, Kyoto 606-8501, Japan. Electronic address: mshinoha@virus.kyoto-u.ac.jp. ^[6] Chromosome Engineering Research Center (CERC), Tottori University, 86 Nishicho, Yonago 683-8503, Japan; Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University, Yonago 683-8503, Japan. Electronic address: kazuki@grape.med.tottori-u.ac.jp. ^[7]

关键词 artificial chromosome karyotype spermatogenesis spermatogonia

主题词动物(Animals);细胞追踪(Cell Tracking);染色体, 合成(Chromosomes, Artificial);基因表达(Gene Expression);基因转移技术(Gene Transfer Techniques);基因, 报告(Genes, Reporter);基因组不稳定性(Genomic Instability);免疫表型分型(Immunophenotyping);男(雄)性(Male);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);表型(Phenotype);精子发生(Spermatogenesis);精原细胞(Spermatogonia)

DOI 10.1016/j.stemcr.2017.08.012

PMID 28943251

发布时间 2022-03-21

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Stem cell reports

2017年9卷4期

1180-1191页

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Transfer of a Mouse Artificial Chromosome into Spermatogonial Stem Cells Generates Transchromosomic Mice.

Stem cell reports

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Stem cell reports

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Transfer of a Mouse Artificial Chromosome into Spermatogonial Stem Cells Generates Transchromosomic Mice.

Stem cell reports

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Stem cell reports

相关期刊

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