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Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data.

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第一作者: Niedzica,Camacho
第一单位: Division of Genetics and Epidemiology, The Institute Of Cancer Research, London, United Kingdom.;Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America.;Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America.
作者单位: Division of Genetics and Epidemiology, The Institute Of Cancer Research, London, United Kingdom.;Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America.;Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America. [1] Cancer Genomics Laboratory, The Francis Crick Institute, London, United Kingdom.;Department of Human Genetics, University of Leuven, Leuven, Belgium. [2] Division of Genetics and Epidemiology, The Institute Of Cancer Research, London, United Kingdom. [3] Uro-Oncology Research Group, Cancer Research UK Cambridge Institute, Cambridge, Cambridgeshire, United Kingdom.;Molecular Diagnostics and Therapeutics Group, University College London, London, United Kingdom. [4] Cancer Genomics Laboratory, The Francis Crick Institute, London, United Kingdom. [5] Norwich Medical School, University of East Anglia, Norwich, Norfolk, United Kingdom. [6] Cancer Genetics Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom. [7] Cancer, Ageing and Somatic Mutation, Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, United Kingdom. [8] Cancer, Ageing and Somatic Mutation, Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, United Kingdom.;Epidemiology & Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America. [9] Uro-Oncology Research Group, Cancer Research UK Cambridge Institute, Cambridge, Cambridgeshire, United Kingdom. [10] Department of Physiology, University of Oxford, Oxford, Oxfordshire, United Kingdom. [11] Department of Oncology, CRUK/MRC Oxford Institute for Radiation Oncology, Oxford, Oxfordshire, United Kingdom. [12] Department of Oncology, CRUK/MRC Oxford Institute for Radiation Oncology, Oxford, Oxfordshire, United Kingdom.;Nuffield Department of Surgical Sciences, University of Oxford, Oxford, Oxfordshire, United Kingdom. [13] Nuffield Department of Surgical Sciences, University of Oxford, Oxford, Oxfordshire, United Kingdom. [14] Uro-Oncology Research Group, Cancer Research UK Cambridge Institute, Cambridge, Cambridgeshire, United Kingdom.;CRUK Cambridge Centre, Early Detection Programme, Urological Malignancies Programme, Hutchison-MRC Research Centre, Cambridge, Cambridgeshire, United Kingdom. [15] Histopathology and in situ hybridization Research Group, Cancer Research UK Cambridge Institute, Cambridge, Cambridgeshire, United Kingdom. [16] Department of Epidemiology, Second Military Medical University, Shanghai, China. [17] Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, United Kingdom. [18] Academic Urology Group, Department of Surgery, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom. [19] School of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America. [20] Faculty of Medicine and Life Sciences and BioMediTech Institute, University of Tampere and Tampere University Hospital, Tampere, Finland. [21] Centre for Molecular Oncology, Barts Cancer Institute, The Barts and London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom. [22] Department of Cellular Pathology and Oxford Biomedical Research Centre, Oxford University Hospitals NHS Trust, Oxford, Oxfordshire, United Kingdom. [23] Cancer, Ageing and Somatic Mutation, Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, United Kingdom.;Oxford Big Data Institute & Oxford Centre for Cancer Gene Research, Wellcome Trust Centre for Human Genetics, Oxford, Oxfordshire, United Kingdom. [24] Statistics and Computational Biology Laboratory, Cancer Research UK Cambridge Institute, Cambridge, Cambridgeshire, United Kingdom.;School of Mathematics and Statistics/School of Medicine, University of St Andrews, St Andrews, Fife, Scotland. [25] HCA Pathology Laboratories, HCA Healthcare, London, United Kingdom. [26] Uro-Oncology Research Group, Cancer Research UK Cambridge Institute, Cambridge, Cambridgeshire, United Kingdom.;Academic Urology Group, Department of Surgery, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom. [27] Division of Genetics and Epidemiology, The Institute Of Cancer Research, London, United Kingdom.;Cancer Genetics Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom. [28] Division of Genetics and Epidemiology, The Institute Of Cancer Research, London, United Kingdom.;Norwich Medical School, University of East Anglia, Norwich, Norfolk, United Kingdom. [29] Norwich Medical School, University of East Anglia, Norwich, Norfolk, United Kingdom.;Organisms and Ecosystems, The Earlham Institute, Norwich, Norfolk, United Kingdom. [30]
DOI 10.1371/journal.pgen.1007001
PMID 28945760
发布时间 2025-05-30
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