Design, Synthesis, and Evaluation of Tetrahydropyrrolo[1,2-<i>c</i>]pyrimidines as Capsid Assembly Inhibitors for HBV Treatment.

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作者： Xiaolin,Li ^[1] ; Kai,Zhou ^[1] ; Haiying,He ^[1] ; Qiong,Zhou ^[1] ; Ya,Sun ^[1] ; Lijuan,Hou ^[1] ; Liang,Shen ^[1] ; Xiaofei,Wang ^[1] ; Yuedong,Zhou ^[1] ; Zhen,Gong ^[1] ; Shibo,He ^[1] ; Huangtao,Jin ^[1] ; Zhengxian,Gu ^[1] ; Shuyong,Zhao ^[2] ; Long,Zhang ^[2] ; Chunyan,Sun ^[2] ; Shansong,Zheng ^[2] ; Zhe,Cheng ^[2] ; Yidong,Zhu ^[2] ; Minghui,Zhang ^[2] ; Jian,Li ^[1] ; Shuhui,Chen ^[1]

作者单位： WuXi AppTec (Shanghai) Co., Ltd., 288 FuTe Zhong Road, Shanghai 200131, P. R. China. ^[1] Shandong Provincial Key Laboratory of Small Molecular Targeted Drugs, Qilu Pharmaceutical Co., Ltd., No. 243 Gong Ye Bei Road, Jinan, Shandong Province 250100, P. R. China. ^[2]

关键词 Hepatitis B virus (HBV)capsid assembly inhibitor tetrahydropyrrolo[1,2-c]pyrimidines

DOI 10.1021/acsmedchemlett.7b00288

PMID 28947946

发布时间 2024-07-21

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