Mechanism of environmentally driven conformational changes that modulate H-NS DNA-bridging activity.

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作者： Ramon A,van der Valk ^[1] ; Jocelyne,Vreede ^[2] ; Liang,Qin ^[1] ; Geri F,Moolenaar ^[1] ; Andreas,Hofmann ^[3] ; Nora,Goosen ^[1] ; Remus T,Dame ^[1]

作者单位： Leiden Institute of Chemistry, Leiden University, Leiden, Netherlands. ^[1] Computational Chemistry, Van 't Hoff Institute for Molecular Sciences, University of Amsterdam, Amsterdam, Netherlands. ^[2] Institute for Theoretical Physics, University of Heidelberg, Heidelberg, Germany. ^[3] Centre for Microbial Cell Biology, Leiden University, Leiden, Netherlands. ^[4]

关键词 E. coli H-NS Hha YdgT bacterial chromatin biophysics chromosomes genes nucleoid structural biology

主题词 DNA(DNA);大肠杆菌蛋白质类(Escherichia coli Proteins);菌毛蛋白质类(Fimbriae Proteins);分子动力学模拟(Molecular Dynamics Simulation);蛋白质结合(Protein Binding);蛋白质构象(Protein Conformation)

DOI 10.7554/eLife.27369

PMID 28949292

发布时间 2023-11-12

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