Patient-specific bolus for range shifter air gap reduction in intensity-modulated proton therapy of head-and-neck cancer studied with Monte Carlo based plan optimization.

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第一作者： Steven,Michiels

第一单位： Laboratory of Experimental Radiotherapy, Department of Oncology, KU Leuven - University of Leuven, Belgium. Electronic address: michiels.steven@kuleuven.be.

作者： Steven,Michiels ^[1] ; Ana Maria,Barragán ^[2] ; Kevin,Souris ^[2] ; Kenneth,Poels ^[3] ; Wouter,Crijns ^[3] ; John A,Lee ^[2] ; Edmond,Sterpin ^[4] ; Sandra,Nuyts ^[5] ; Karin,Haustermans ^[5] ; Tom,Depuydt ^[6]

作者单位： Laboratory of Experimental Radiotherapy, Department of Oncology, KU Leuven - University of Leuven, Belgium. Electronic address: michiels.steven@kuleuven.be. ^[1] Center of Molecular Imaging, Radiotherapy and Oncology, Institut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Belgium. ^[2] Department of Radiation Oncology, University Hospitals Leuven, Belgium. ^[3] Laboratory of Experimental Radiotherapy, Department of Oncology, KU Leuven - University of Leuven, Belgium; Center of Molecular Imaging, Radiotherapy and Oncology, Institut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Belgium. ^[4] Laboratory of Experimental Radiotherapy, Department of Oncology, KU Leuven - University of Leuven, Belgium; Department of Radiation Oncology, University Hospitals Leuven, Belgium. ^[5] Laboratory of Experimental Radiotherapy, Department of Oncology, KU Leuven - University of Leuven, Belgium; Department of Radiation Oncology, University Hospitals Leuven, Belgium. Electronic address: tom.depuydt@kuleuven.be. ^[6]

关键词 3D printing Head-and-neck cancer IMPT Oropharyngeal cancer Proton therapy Range shifting