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Systematic analysis of human telomeric dysfunction using inducible telosome/shelterin CRISPR/Cas9 knockout cells.

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第一作者： Hyeung,Kim

第一单位： Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX, USA.

作者： Hyeung,Kim ^[1] ; Feng,Li ^[2] ; Quanyuan,He ^[1] ; Tingting,Deng ^[2] ; Jun,Xu ^[3] ; Feng,Jin ^[4] ; Cristian,Coarfa ^[4] ; Nagireddy,Putluri ^[4] ; Dan,Liu ^[5] ; Zhou,Songyang ^[6]

作者单位： Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX, USA. ^[1] Key Laboratory of Gene Engineering of the Ministry of Education and State Key Laboratory for Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China. ^[2] Cell-Based Assay Screening Service Core, Baylor College of Medicine, Houston, TX, USA. ^[3] Department of Molecular and Cellular Biology and Advanced Technology Core, Baylor College of Medicine, Houston, TX, USA. ^[4] Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX, USA.;Cell-Based Assay Screening Service Core, Baylor College of Medicine, Houston, TX, USA. ^[5] Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX, USA.;Key Laboratory of Gene Engineering of the Ministry of Education and State Key Laboratory for Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China. ^[6]

关键词 CRISPR/Cas9 POT1 isoform inducible knockout metabolism telomere telosome/shelterin

DOI 10.1038/celldisc.2017.34

PMID 28955502

发布时间 2023-08-08

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Systematic analysis of human telomeric dysfunction using inducible telosome/shelterin CRISPR/Cas9 knockout cells.

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Systematic analysis of human telomeric dysfunction using inducible telosome/shelterin CRISPR/Cas9 knockout cells.

Cell discovery

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Cell discovery

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