Direct coupling of the HER4 intracellular domain (4ICD) and STAT5A signaling is required to induce mammary epithelial cell differentiation.
第一作者:
Wen,Han
第一单位:
Department of Cell and Molecular Biology, Tulane University, New Orleans, LA 70118, USA.
作者:
关键词
4ICD, HER4 intracellular domainATCC, American type culture collectionEGF, epidermal growth factorEGFP, enhanced green fluorescent proteinEGFR, epidermal growth factor familyEGFR-familyERα, estrogen receptor alphaFBS, fetal bovine serumGene expressionHEK, human embryonic kidneyHER4/ERBB4HRGα, heregulin alphaHRGα1, heregulin beta 1Mammary epithelial differentiationNLS, nuclear localization signalPCR, polymerase chain reactionPI3K, phosphoinositide 3-kinaseRIP, regulated intramembrane cleavageRT, reverse transcriptionRTK, receptor tyrosine kinaseSH2, src homology 2STAT5ASTAT5A, signal transducer and activator of transcription 5ATACE, tumor necrosis factor-α-converting enzymeTransactivationWAP, whey acidic proteinYAP, yes-associated protein
DOI
10.1016/j.bbrep.2016.07.015
PMID
28955922
发布时间
2020-09-30
- 浏览2
Biochemistry and biophysics reports
2016年7卷
323-327页
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