p-Benzoquinone initiates non-invasive urothelial cancer through aberrant tyrosine phosphorylation of EGFR, MAP kinase activation and cell cycle deregulation: Prevention by vitamin C.
作者:
关键词
Aberrant EGFR activationBax, BCL2-associated X proteinBcl-2, B-cell lymphoma 2CIS, carcinoma in situCS, cigarette smokeCarcinoma in situCell cycle deregulationDNPH, 2 4-dinitrophenylhydrazineDysplasiaEGFR, epidermal growth factor receptorGAPDH, glyceraldehyde 3-phosphate dehydrogenaseIARC, International Agency for Research on CancerMAPK, mitogen activated protein kinasePAHs, polycyclic aromatic hydrocarbonsPBS, phosphate buffered salineROS, reactive oxygen speciesSDS PAGE, sodium dodecyl sulfate polyacrylamide gel electrophoresisTUNEL, terminal deoxynucleotidyl transferase dUTP nick end labellingUC, urothelial carcinomaVitamin CWHO, World Health Organizationp-BQ, p-benzoquinonep-BSQ, p-benzosemiquinonep-Benzoquinone
DOI
10.1016/j.toxrep.2017.06.005
PMID
28959653
发布时间
2022-04-08
- 浏览4
Toxicology reports
2017年4卷
296-305页
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文