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β1 integrin-dependent Rac/group I PAK signaling mediates YAP activation of Yes-associated protein 1 (YAP1) via NF2/merlin.

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第一作者： Hiba,Sabra

第一单位： From the Institute for Advanced Bioscience, Université Grenoble Alpes, INSERM 1209, CNRS 5309, F-38042 Grenoble, France.

作者： Hiba,Sabra ^[1] ; Molly,Brunner ^[1] ; Vinay,Mandati ^[2] ; Bernhard,Wehrle-Haller ^[3] ; Dominique,Lallemand ^[4] ; Anne-Sophie,Ribba ^[1] ; Genevieve,Chevalier ^[1] ; Philippe,Guardiola ^[5] ; Marc R,Block ^[1] ; Daniel,Bouvard ^[6]

作者单位： From the Institute for Advanced Bioscience, Université Grenoble Alpes, INSERM 1209, CNRS 5309, F-38042 Grenoble, France. ^[1] the Department of Cancer Biology, Scripps Research Institute, Jupiter, Florida 33458. ^[2] the Department of Cell Physiology and Metabolism, Centre Médical Universitaire, University of Geneva, CH-1211 Geneva, Switzerland. ^[3] the Ecole Polytechnique, Department of Biochemistry, CNRS 7654, F-91128 Palaiseau, France, and. ^[4] the Centre Hospitalier Universitaire and Université d'Angers, Plateform, Institute for Biological Health, Transcriptome and Epigenomic, F-49933 Angers, France. ^[5] From the Institute for Advanced Bioscience, Université Grenoble Alpes, INSERM 1209, CNRS 5309, F-38042 Grenoble, France, daniel.bouvard@univ-grenoble-alpes.fr. ^[6]

关键词 Rac (Rac GTPase)adhesion cell proliferation integrin yes-associated protein (YAP)