PARP inhibitors protect against sex- and AAG-dependent alkylation-induced neural degeneration.

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作者： Mariacarmela,Allocca ^[1] ; Joshua J,Corrigan ^[2] ; Kimberly R,Fake ^[1] ; Jennifer A,Calvo ^[2] ; Leona D,Samson ^[1]

作者单位： Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. ^[1] Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. ^[2] Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. ^[3] David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. ^[4]

关键词 AAG/MPG PARP inhibitors PARP1 alkylating agents retinal and cerebellar degeneration

DOI 10.18632/oncotarget.19844

PMID 28978150

发布时间 2019-11-20

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