Acquired Resistance to FGFR Inhibitor in Diffuse-Type Gastric Cancer through an AKT-Independent PKC-Mediated Phosphorylation of GSK3β.
作者:
主题词
动物(Animals);细胞凋亡(Apoptosis);细胞系, 肿瘤(Cell Line, Tumor);人类(Humans);小鼠(Mice);小鼠, 近交NOD(Mice, Inbred NOD);磷酰化(Phosphorylation);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);受体, 成纤维细胞生长因子, 2型(Receptor, Fibroblast Growth Factor, Type 2);信号传导(Signal Transduction);胃肿瘤(Stomach Neoplasms);转染(Transfection)
DOI
10.1158/1535-7163.MCT-17-0367
PMID
28978722
发布时间
2020-09-30
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Molecular cancer therapeutics
232-242页
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