Therapeutic approaches to target alpha-synuclein pathology.

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第一作者： Patrik,Brundin

第一单位： Center for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, MI 49503, USA. Electronic address: Patrik.Brundin@vai.org.

作者： Patrik,Brundin ^[1] ; Kuldip D,Dave ^[2] ; Jeffrey H,Kordower ^[3]

作者单位： Center for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, MI 49503, USA. Electronic address: Patrik.Brundin@vai.org. ^[1] The Michael J Fox Foundation, New York, NY 10017, USA. ^[2] Center for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, MI 49503, USA; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA. ^[3]

关键词 Alpha-synuclein Biomarker Clinical Trial Dementia with Lewy bodies Immunotherapy Multiple system atrophy Parkinson's disease Protein aggregation Therapy

主题词动物(Animals);疾病模型, 动物(Disease Models, Animal);人类(Humans);多系统萎缩(Multiple System Atrophy);神经元(Neurons);帕金森病(Parkinson Disease);α突触核蛋白(alpha-Synuclein)

DOI 10.1016/j.expneurol.2017.10.003

PMID 28987463

发布时间 2020-02-25

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准确一般字义偏差语意偏离译文作用小提交