Supraphysiologic control over HIV-1 replication mediated by CD8 T cells expressing a re-engineered CD4-based chimeric antigen receptor.

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第一作者： Rachel S,Leibman

第一单位： Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

作者： Rachel S,Leibman ^[1] ; Max W,Richardson ^[2] ; Christoph T,Ellebrecht ^[1] ; Colby R,Maldini ^[2] ; Joshua A,Glover ^[3] ; Anthony J,Secreto ^[1] ; Irina,Kulikovskaya ^[2] ; Simon F,Lacey ^[4] ; Sarah R,Akkina ^[4] ; Yanjie,Yi ^[2] ; Farida,Shaheen ^[2] ; Jianbin,Wang ^[1] ; Keith A,Dufendach ^[4] ; Michael C,Holmes ^[4] ; Ronald G,Collman ^[5] ; Aimee S,Payne ^[1] ; James L,Riley ^[2]

作者单位： Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America. ^[1] Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America. ^[2] Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America. ^[3] Department of Medicine and Center for AIDS Research, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America. ^[4] Sangamo BioSciences Inc., Richmond, California, United States of America. ^[5]