Inhibition of Cdk5 rejuvenates inhibitory circuits and restores experience-dependent plasticity in adult visual cortex.

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作者： Yue,Li ^[1] ; Laijian,Wang ^[2] ; Xinxin,Zhang ^[1] ; Mengyao,Huang ^[2] ; Sitong,Li ^[1] ; Xinxing,Wang ^[1] ; Lin,Chen ^[1] ; Bin,Jiang ^[3] ; Yupeng,Yang ^[4]

作者单位： CAS Key Laboratory of Brain Function and Diseases, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, China. ^[1] Guangdong Province Key Laboratory of Brain Function and Disease, Faculty of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong 510080, China. ^[2] Guangdong Province Key Laboratory of Brain Function and Disease, Faculty of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong 510080, China. Electronic address: jiangb3@mail.sysu.edu.cn. ^[3] CAS Key Laboratory of Brain Function and Diseases, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, China. Electronic address: yangyp@ustc.edu.cn. ^[4]

关键词 Adult plasticity Cdk5 Cortical circuits GABAergic inhibition LTP iLTD