The reduced osteogenic potential of Nf1-deficient osteoprogenitors is EGFR-independent.

导出 OA

翻译打印收藏纠错

作者： S E,Tahaei ^[1] ; G,Couasnay ^[2] ; Y,Ma ^[2] ; N,Paria ^[3] ; J,Gu ^[4] ; B F,Lemoine ^[4] ; X,Wang ^[4] ; J J,Rios ^[5] ; F,Elefteriou ^[6]

作者单位： Department of Pharmacology, Vanderbilt University, Nashville, TN, United States; Department of Orthopedic Surgery, Baylor College of Medicine, Houston, TX, United States. ^[1] Department of Orthopedic Surgery, Baylor College of Medicine, Houston, TX, United States. ^[2] Seay Center for Musculoskeletal Research, Texas Scottish Rite Hospital for Children, Dallas, TX, United States. ^[3] Baylor Institute for Immunology Research, Dallas, TX, United States. ^[4] Seay Center for Musculoskeletal Research, Texas Scottish Rite Hospital for Children, Dallas, TX, United States; Department of Pediatrics, UT Southwestern Medical Center, Dallas, TX, United States; McDermott Center for Human Growth and Development, UT Southwestern Medical Center, Dallas, TX, United States; Department of Orthopaedic Surgery, UT Southwestern Medical Center, Dallas, TX, United States. ^[5] Department of Orthopedic Surgery, Baylor College of Medicine, Houston, TX, United States; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, United States. Electronic address: florente@bcm.edu. ^[6]

关键词 Bone marrow stromal cells Differentiation EGFR Epiregulin Neurofibromatosis type 1 Osteoblasts RAS-MAPK signaling