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Development of photoaffinity derivatives of the antitumor macrolide aplyronine A, a PPI-inducer between actin and tubulin.

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第一作者： Masaki,Kita

第一单位： Graduate School of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8571, Japan; Graduate School of Bioagricultural Sciences, Nagoya University, Chikusa, Nagoya 464-8601, Japan; JST-PRESTO, Furo-cho, Chikusa, Nagoya 464-8601, Japan. Electronic address: mkita@agr.nagoya-u.ac.jp.

作者： Masaki,Kita ^[1] ; Kota,Yamagishi ^[2] ; Kota,Tsuchiya ^[2] ; Yu,Seguchi ^[2] ; Hiroki,Nakane ^[2] ; Hideo,Kigoshi ^[3]

作者单位： Graduate School of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8571, Japan; Graduate School of Bioagricultural Sciences, Nagoya University, Chikusa, Nagoya 464-8601, Japan; JST-PRESTO, Furo-cho, Chikusa, Nagoya 464-8601, Japan. Electronic address: mkita@agr.nagoya-u.ac.jp. ^[1] Graduate School of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8571, Japan. ^[2] Graduate School of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8571, Japan. Electronic address: kigoshi@chem.tsukuba.ac.jp. ^[3]

关键词 Actin Antitumor natural products Photoaffinity probe Protein–protein interaction Tubulin