Development of Adenosine Deaminase-Specific IgY Antibodies: Diagnostic and Inhibitory Application.

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作者： Agnieszka,Łupicka-Słowik ^[1] ; Mateusz,Psurski ^[2] ; Renata,Grzywa ^[1] ; Kamila,Bobrek ^[3] ; Patrycja,Smok ^[1] ; Maciej,Walczak ^[1] ; Andrzej,Gaweł ^[3] ; Tadeusz,Stefaniak ^[4] ; Józef,Oleksyszyn ^[1] ; Marcin,Sieńczyk ^[5]

作者单位： Faculty of Chemistry, Division of Medicinal Chemistry and Microbiology, Wroclaw University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370, Wrocław, Poland. ^[1] Laboratory of Experimental Anticancer Therapy, Department of Experimental Oncology, Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Weigla 12, 53-114, Wrocław, Poland. ^[2] Faculty of Veterinary Medicine, Department of Epizootiology and Clinic of Bird and Exotic Animals, Wroclaw University of Environmental and Life Sciences, Pl. Grunwaldzki 45, 50-366, Wrocław, Poland. ^[3] Faculty of Veterinary Medicine, Department of Immunology, Pathophysiology and Veterinary Preventive Medicine, Wroclaw University of Environmental and Life Sciences, Norwida 31, 50-375, Wrocław, Poland. ^[4] Faculty of Chemistry, Division of Medicinal Chemistry and Microbiology, Wroclaw University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370, Wrocław, Poland. marcin.sienczyk@pwr.edu.pl. ^[5]

关键词 Adenosine deaminase (ADA)Affinity purification Anti-adenosine deaminase antibody ELISA Egg yolk immunoglobulin (IgY)Enzyme inhibition