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Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson's disease.

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作者单位: Department of Neurodegenerative Diseases, Center of Neurology and Hertie-Institute for Clinical Brain Research, University of Tübingen and German Centre for Neurodegenerative Diseases, Tübingen, Germany. [1] Medical University Vienna, Department of Neurology, Vienna, Austria. [2] Department of Women's Health, Research Institute for Women's Health, University of Tübingen, Tübingen, Germany. [3] University of Tübingen, Interfaculty Institute of Biochemistry, Tübingen, Germany. [4] Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-sur-Alzette, Luxembourg. [5] Graduate Training Centre of Neuroscience, International Max Planck Research School, Tübingen, Germany. [6] University of Geneva, Department of Cell Biology, Geneva, Switzerland. [7] Department of Psychiatry and Psychotherapie, University Hospital Tübingen, Germany. [8] University of Tübingen, Interfaculty Institute for Cell Biology, Proteome Center Tübingen, Tübingen, Germany. [9] University of Tübingen, Interfaculty Institute of Cell Biology, Unit of Molecular Biology, Tübingen, Germany. [10] University of Tübingen, Institute of Medical Genetics and Applied Genomics, Tübingen, Germany. [11] MRC Toxicology Unit, University of Leicester, Leicester, UK. [12] Department of Cell and Tissue Engineering, Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB Stuttgart, Germany. [13] Department of Medicine/ Cardiology, CVRL, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. [14] Centre for Genetic Epidemiology, Institute for Clinical Epidemiology and Applied Biometry, University of Tübingen, Germany. [15] Parkinson Research Clinic, Centre Hospitalier de Luxembourg (CHL), Luxembourg. [16]
DOI 10.1093/brain/awx202
PMID 29050400
发布时间 2022-01-29
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Brain : a journal of neurology

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