Pharmacological targeting of apelin impairs glioblastoma growth.

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作者： Elizabeth,Harford-Wright ^[1] ; Gwennan,Andre-Gregoire ^[2] ; Kathryn A,Jacobs ^[1] ; Lucas,Treps ^[1] ; Sophie,Le Gonidec ^[2] ; Heloise M,Leclair ^[3] ; Sara,Gonzalez-Diest ^[1] ; Quentin,Roux ^[2] ; François,Guillonneau ^[1] ; Delphine,Loussouarn ^[2] ; Lisa,Oliver ^[1] ; François M,Vallette ^[4] ; Fabienne,Foufelle ^[5] ; Philippe,Valet ^[6] ; Anthony P,Davenport ^[5] ; Robert C,Glen ^[6] ; Nicolas,Bidere ^[6] ; Julie,Gavard ^[7]

作者单位： CRCINA, Inserm, Team SOAP, CNRS, Universite de Nantes, Nantes, France. ^[1] Institut Cochin, Team SOAP, Inserm, CNRS, Universite Paris Descartes, Paris, France. ^[2] I2MC, Inserm, Universite Paul Sabatier, Toulouse, France. ^[3] 3P5 Proteomics Facility of the Universite Paris Descartes, Paris, France. ^[4] Centre Hospitalier Universitaire (CHU) de Nantes, Nantes, France. ^[5] CRCINA, Inserm, Universite de Nantes, Nantes, France. ^[6] Institut de Cancérologie de l'Ouest, René Gauducheau, St Herblain, France. ^[7] Centre de Recherches des Cordeliers, Inserm, Universite Paris Descartes, Paris, France. ^[8] Experimental Medicine and Immunotherapeutics, University of Cambridge, Cambridge, UK. ^[9] The Centre for Molecular Informatics, Department of Chemistry, University of Cambridge, Cambridge, UK. ^[10] Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, UK. ^[11]

关键词 APJ antagonist apelin glioblastoma initiating cells vascular niche