MethylQuant: A Tool for Sensitive Validation of Enzyme-Mediated Protein Methylation Sites from Heavy-Methyl SILAC Data.

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作者： Aidan P,Tay ^[1] ; Vincent,Geoghegan ^[2] ; Daniel,Yagoub ^[1] ; Marc R,Wilkins ^[1] ; Gene,Hart-Smith ^[1]

作者单位： NSW Systems Biology Initiative, School of Biotechnology and Biomolecular Sciences, University of New South Wales , Sydney, New South Wales 2052, Australia. ^[1] Centre for Immunology and Infection, University of York , Heslington, York YO10 5DD, United Kingdom. ^[2]

关键词 MethylQuant false discovery rate (FDR)heavy-methyl SILAC metabolic labeling post-translational methylation proteomics quality control quantitative proteomics software

主题词结合部位(Binding Sites);同位素标记(Isotope Labeling);甲基化(Methylation);蛋白质加工, 转译后(Protein Processing, Post-Translational);蛋白质组学(Proteomics);敏感性与特异性(Sensitivity and Specificity)

DOI 10.1021/acs.jproteome.7b00601

PMID 29057651

发布时间 2021-02-18

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