首页> Annals of oncology : official journal of the European Society for Medical Oncology> A prospective genome-wide study of prostate cancer metastases reveals association of wnt pathway activation and increased cell cycle proliferation with primary resistance to abiraterone acetate-prednisone.

A prospective genome-wide study of prostate cancer metastases reveals association of wnt pathway activation and increased cell cycle proliferation with primary resistance to abiraterone acetate-prednisone.

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第一作者： L,Wang

第一单位： Division of Biomedical Statistics and Informatics, Department of Health Sciences, Rochester, USA; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, USA.

作者： L,Wang ^[1] ; S M,Dehm ^[2] ; D W,Hillman ^[3] ; H,Sicotte ^[3] ; W,Tan ^[4] ; M,Gormley ^[5] ; V,Bhargava ^[5] ; R,Jimenez ^[6] ; F,Xie ^[7] ; P,Yin ^[7] ; S,Qin ^[7] ; F,Quevedo ^[8] ; B A,Costello ^[8] ; H C,Pitot ^[8] ; T,Ho ^[9] ; A H,Bryce ^[9] ; Z,Ye ^[10] ; Y,Li ^[3] ; P,Eiken ^[11] ; P T,Vedell ^[3] ; P,Barman ^[3] ; B P,McMenomy ^[11] ; T D,Atwell ^[11] ; R E,Carlson ^[3] ; M,Ellingson ^[12] ; B W,Eckloff ^[13] ; R,Qin ^[3] ; F,Ou ^[3] ; S N,Hart ^[3] ; H,Huang ^[10] ; J,Jen ^[14] ; E D,Wieben ^[13] ; K R,Kalari ^[3] ; R M,Weinshilboum ^[7] ; L,Wang ^[15] ; M,Kohli ^[16]

作者单位： Division of Biomedical Statistics and Informatics, Department of Health Sciences, Rochester, USA; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, USA. ^[1] Masonic Cancer Center, University of Minnesota, Minneapolis, USA; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, USA; Department of Urology, University of Minnesota, Minneapolis, USA. ^[2] Division of Biomedical Statistics and Informatics, Department of Health Sciences, Rochester, USA. ^[3] Department of Medicine, Mayo Clinic, Jacksonville, USA. ^[4] Janssen Research and Development, Spring House, Philadelphia, USA. ^[5] Department of Pathology and Lab Medicine, Mayo Clinic, Rochester, USA. ^[6] Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, USA. ^[7] Department of Oncology, Mayo Clinic, Rochester, USA. ^[8] Department of Medicine, Mayo Clinic, Scottsdale, USA. ^[9] Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, USA. ^[10] Department of Radiology, Mayo Clinic, Rochester, USA. ^[11] Medical Genetics, Mayo Clinic, Rochester, USA. ^[12] Medical Genome Facility, Mayo Clinic, Rochester, USA. ^[13] Medical Genome Facility, Mayo Clinic, Rochester, USA; Division of Experimental Pathology and Laboratory Medicine, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, USA; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, USA. ^[14] Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, USA. Electronic address: wang.liewei@mayo.edu. ^[15] Department of Oncology, Mayo Clinic, Rochester, USA. Electronic address: kohli.manish@mayo.edu. ^[16]