Characterization of the transcriptional and metabolic responses of pediatric high grade gliomas to mTOR-HIF-1α axis inhibition.

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第一作者： Aurélia,Nguyen

第一单位： Laboratory EA 3430, Progression Tumorale et Micro-Environnement, Approches Translationnelles et Epidémiologie, University of Strasbourg, Strasbourg, France.

作者： Aurélia,Nguyen ^[1] ; François Marie,Moussallieh ^[2] ; Alan,Mackay ^[3] ; A Ercument,Cicek ^[4] ; Andres,Coca ^[5] ; Marie Pierre,Chenard ^[6] ; Noelle,Weingertner ^[7] ; Benoit,Lhermitte ^[7] ; Eric,Letouzé ^[8] ; Eric,Guérin ^[1] ; Erwan,Pencreach ^[1] ; Sarah,Jannier ^[9] ; Dominique,Guenot ^[1] ; Izzie Jacques,Namer ^[2] ; Chris,Jones ^[3] ; Natacha,Entz-Werlé ^[9]

作者单位： Laboratory EA 3430, Progression Tumorale et Micro-Environnement, Approches Translationnelles et Epidémiologie, University of Strasbourg, Strasbourg, France. ^[1] Department of Nuclear Medicine, University Hospital of Strasbourg, Strasbourg, France. ^[2] Institute of Cancer Research, Sutton, Surrey, United Kingdom. ^[3] Computational Biology Department, Carnegie Mellon University, Pittsburgh, PA, USA.;Computer Engineering Department, Bilkent University, Cankaya, Ankara, Turkey. ^[4] Department of Neurosurgery, University Hospital of Strasbourg, Strasbourg, France. ^[5] Department of Pathology, University Hospital of Strasbourg, Strasbourg, France.;Centre de Ressources Biologiques, University Hospital of Strasbourg, Strasbourg, France. ^[6] Department of Pathology, University Hospital of Strasbourg, Strasbourg, France. ^[7] Programme Cartes d'Identité des Tumeurs, Ligue Nationale Contre Le Cancer, Paris, France. ^[8] Laboratory EA 3430, Progression Tumorale et Micro-Environnement, Approches Translationnelles et Epidémiologie, University of Strasbourg, Strasbourg, France.;Department of Pediatric Onco-hematology, University Hospital of Strasbourg, Strasbourg, France. ^[9]

关键词 HIF1alpha high grade glioma mTor pediatric targets

DOI 10.18632/oncotarget.16500

PMID 29069732

发布时间 2019-11-20

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2017年8卷42期

71597-71617页

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Characterization of the transcriptional and metabolic responses of pediatric high grade gliomas to mTOR-HIF-1α axis inhibition.

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Characterization of the transcriptional and metabolic responses of pediatric high grade gliomas to mTOR-HIF-1α axis inhibition.

Oncotarget

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Oncotarget

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