Antithrombotic therapy in atrial fibrillation associated with valvular heart disease: a joint consensus document from the European Heart Rhythm Association (EHRA) and European Society of Cardiology Working Group on Thrombosis, endorsed by the ESC Working Group on Valvular Heart Disease, Cardiac Arrhythmia Society of Southern Africa (CASSA), Heart Rhythm Society (HRS), Asia Pacific Heart Rhythm Society (APHRS), South African Heart (SA Heart) Association and Sociedad Latinoamericana de Estimulación Cardíaca y Electrofisiología (SOLEACE).

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第一作者： Gregory Y H,Lip

第一单位： Institute of Cardiovascular Sciences, University of Birmingham and Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Denmark.

作者： Gregory Y H,Lip ^[1] ; Jean Philippe,Collet ^[2] ; Raffaele de,Caterina ^[3] ; Laurent,Fauchier ^[4] ; Deirdre A,Lane ^[5] ; Torben B,Larsen ^[6] ; Francisco,Marin ^[7] ; Joao,Morais ^[8] ; Calambur,Narasimhan ^[9] ; Brian,Olshansky ^[10] ; Luc,Pierard ^[11] ; Tatjana,Potpara ^[12] ; Nizal,Sarrafzadegan ^[13] ; Karen,Sliwa ^[14] ; Gonzalo,Varela ^[15] ; Gemma,Vilahur ^[16] ; Thomas,Weiss ^[17] ; Giuseppe,Boriani ^[18] ; Bianca,Rocca ^[19] ; ESC Scientific Document Group

作者单位： Institute of Cardiovascular Sciences, University of Birmingham and Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Denmark. ^[1] Sorbonne Université Paris 6, ACTION Study Group, Institut De Cardiologie, Groupe Hôpital Pitié-Salpetrière (APHP), INSERM UMRS 1166, Paris, France. ^[2] Institute of Cardiology, 'G. D'Annunzio' University, Chieti, Italy. ^[3] Centre Hospitalier Universitaire Trousseau et Faculté de Medicinde, Université François Rabelais, Tours, France. ^[4] Institute of Cardiovascular Sciences, University of Birmingham, United Kingdom; and Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. ^[5] Thrombosis Research Unit,Department of Clinical Medicine, Aalborg University Hospital, Aalborg, Denmark. ^[6] Hospital Universitario Virgen de la Arrixaca, Murcia, Spain. ^[7] Department of Cardiology, Leiria Hospital Centre, Leiria, Portugal. ^[8] Department of Cardiac Electrophysiology, Care Hospital, Hyderabad, India. ^[9] Mercy Hospital, Mason City, Iowa, USA. ^[10] Department of Cardiology, University Hospital Sart-Tilman, Liege, Belgium. ^[11] School of Medicine, Belgrade University; Cardiology Clinic, Clinical Center of Serbia, Belgrade, Serbia. ^[12] Isfahan Cardiovascular Research Center (WHO Collaborating Center), Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran and School of Population and Public Health, University of British Columbia, Vancouver, Canada. ^[13] Hatter Institute for Cardiovascular Research in Africa, Faculty of Health Sciences, University of Cape Town, South Africa; and Mary McKillop Institute, ACU, Melbourne, Australia. ^[14] Servicio de Electrofisiología, Centro Cardiovascular Casa de Galicia, Hidalgos, Uruguay. ^[15] Cardiovascular Science Institute - ICCC, IIB-Sant Pau, CiberCV, Hospital de Sant Pau, Barcelona, Spain. ^[16] Medical Department For Cardiology and Intensive Care, Wilhelminenhospital, and Medical Faculty Sigmund Freud University, Vienna, Austria. ^[17] Cardiology Department, University of Modena and Reggio Emilia, Policlinico di Modena, Modena, Italy. ^[18] Institute of Pharmacology, Catholic University School of Medicine, Rome, Italy. ^[19]

关键词 Anticoagulation Atrial fibrillation Mechanical prosthetic heart valves Mitral stenosis Non-vitamin K antagonist oral anticoagulants Pregnancy Stroke Stroke prevention Thrombo-embolism Valvular heart disease Vitamin K antagonists