The BRAIN Initiative Cell Census Consortium: Lessons Learned toward Generating a Comprehensive Brain Cell Atlas.

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第一作者： Joseph R,Ecker

第一单位： Genomic Analysis Laboratory and Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

作者： Joseph R,Ecker ^[1] ; Daniel H,Geschwind ^[2] ; Arnold R,Kriegstein ^[3] ; John,Ngai ^[4] ; Pavel,Osten ^[5] ; Damon,Polioudakis ^[2] ; Aviv,Regev ^[6] ; Nenad,Sestan ^[7] ; Ian R,Wickersham ^[8] ; Hongkui,Zeng ^[9]

作者单位： Genomic Analysis Laboratory and Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA 92037, USA. ^[1] Program in Neurogenetics, Departments of Neurology and Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA. ^[2] Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA. ^[3] Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, QB3 Functional Genomics Laboratory, University of California, Berkeley, Berkeley, CA 94720, USA. Electronic address: jngai@berkeley.edu. ^[4] Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA. ^[5] Klarman Cell Observatory, Broad Institute of MIT and Harvard, Department of Biology, Koch Institute of Integrative Cancer Research, and Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02142, USA. ^[6] Departments of Neuroscience, Genetics, Psychiatry and Comparative Medicine, Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale Child Study Center, Kavli Institute for Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA. ^[7] McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. ^[8] Allen Institute for Brain Science, Seattle, WA 98109, USA. ^[9]

关键词 BRAIN initiative anatomy cell census connectivity electrophysiology human brain mouse brain single-cell RNA-seq single-cell epigenomics single-cell transcriptomics

主题词动物(Animals);图集(主题)(Atlases as Topic);脑(Brain);脑图(Brain Mapping);人类(Humans);神经网(Nerve Net);试点项目(Pilot Projects)

DOI 10.1016/j.neuron.2017.10.007

PMID 29096072

发布时间 2024-06-04

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