Mucosa-associated invariant T cells link intestinal immunity with antibacterial immune defects in alcoholic liver disease.

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作者： Antonio,Riva ^[1] ; Vishal,Patel ^[2] ; Ayako,Kurioka ^[1] ; Hannah C,Jeffery ^[2] ; Gavin,Wright ^[3] ; Sarah,Tarff ^[4] ; Debbie,Shawcross ^[5] ; Jennifer M,Ryan ^[6] ; Alexander,Evans ^[6] ; Sarah,Azarian ^[2] ; Jasmohan S,Bajaj ^[3] ; Andrew,Fagan ^[3] ; Vinood,Patel ^[7] ; Kosha,Mehta ^[1] ; Carlos,Lopez ^[8] ; Marieta,Simonova ^[8] ; Krum,Katzarov ^[9] ; Tanya,Hadzhiolova ^[9] ; Slava,Pavlova ^[9] ; Julia A,Wendon ^[10] ; Ye Htun,Oo ^[10] ; Paul,Klenerman ^[10] ; Roger,Williams ^[10] ; Shilpa,Chokshi ^[3]

作者单位： Institute of Hepatology London, Foundation for Liver Research, London, UK. ^[1] Division of Transplantation, Immunology and Mucosal Biology, Faculty of Life Sciences and Medicine, King's College London, London, UK. ^[2] Institute of Liver Studies, King's College London, London, UK. ^[3] Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK. ^[4] Centre for Liver Research and NIHR BRU in Liver Disease, University of Birmingham, Birmingham, UK. ^[5] Department of Gastroenterology, Basildon University Hospital, Basildon, UK. ^[6] Department of Gastroenterology, Royal Berkshire Hospital, Reading, UK. ^[7] Department of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and McGuire VAMC, Richmond, Virginia, USA. ^[8] Department of Biomedical Sciences, University of Westminster, London, UK. ^[9] Department of Gastroenterology, Military Medical Academy, Sofia, Bulgaria. ^[10]

关键词 alcoholic liver disease bacterial translocation inflammation mucosal immunity t lymphocytes