Modulation of the Interleukin-21 Pathway with Interleukin-4 Distinguishes Common Variable Immunodeficiency Patients with More Non-infectious Clinical Complications.

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第一作者： Marylin,Desjardins

第一单位： Division of Allergy and Immunology, Department of Paediatrics, McGill University Health Centre, Montreal, Quebec, Canada. marylin.desjardins@mcgill.ca.

作者： Marylin,Desjardins ^[1] ; Marianne,Béland ^[2] ; Marieme,Dembele ^[3] ; Duncan,Lejtenyi ^[4] ; Jean-Phillipe,Drolet ^[4] ; Martine,Lemire ^[5] ; Christos,Tsoukas ^[6] ; Moshe,Ben-Shoshan ^[7] ; Francisco J D,Noya ^[7] ; Reza,Alizadehfar ^[5] ; Christine T,McCusker ^[5] ; Bruce D,Mazer ^[5]

作者单位： Division of Allergy and Immunology, Department of Paediatrics, McGill University Health Centre, Montreal, Quebec, Canada. marylin.desjardins@mcgill.ca. ^[1] Meakins-Christie Laboratories of the Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada. marylin.desjardins@mcgill.ca. ^[2] Centre for Translational Biology, Research Institute of the McGill University Health Centre, Block E, 1001 Decarie Boulevard, Montreal, Quebec, H4A 3J1, Canada. marylin.desjardins@mcgill.ca. ^[3] Meakins-Christie Laboratories of the Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada. ^[4] Division of Allergy and Immunology, Department of Paediatrics, McGill University Health Centre, Montreal, Quebec, Canada. ^[5] Division of Allergy and Clinical Immunology, Department of Medicine, Centre Hospitalier Universitaire de Quebec, Quebec City, Quebec, Canada. ^[6] Division of Allergy & Clinical Immunology, Department of Medicine, McGill University Health Centre, Montreal, Quebec, Canada. ^[7]

关键词 B lymphocytes Common Variable Immunodeficiency antibody production humoral immune response interleukin-21 interleukin-4