Machine learning model for sequence-driven DNA G-quadruplex formation.

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作者： Aleksandr B,Sahakyan ^[1] ; Vicki S,Chambers ^[1] ; Giovanni,Marsico ^[1] ; Tobias,Santner ^[2] ; Marco,Di Antonio ^[1] ; Shankar,Balasubramanian ^[1]

作者单位： Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. ^[1] Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK. ^[2] Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. sb10031@cam.ac.uk. ^[3] Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK. sb10031@cam.ac.uk. ^[4] School of Clinical Medicine, University of Cambridge, Cambridge, CB2 0SP, UK. sb10031@cam.ac.uk. ^[5]

主题词碱基序列(Base Sequence);计算机模拟(Computer Simulation);G四链体(G-Quadruplexes);基因组, 人(Genome, Human);人类(Humans)

DOI 10.1038/s41598-017-14017-4

PMID 29109402

发布时间 2024-02-10

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