首页> Cancer cell> Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors.

Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors.

导出 OA

翻译打印收藏纠错

第一作者： Vinit,Kumar

第一单位： Immunology, Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, PA 19104, USA.

作者： Vinit,Kumar ^[1] ; Laxminarasimha,Donthireddy ^[1] ; Douglas,Marvel ^[1] ; Thomas,Condamine ^[1] ; Fang,Wang ^[1] ; Sergio,Lavilla-Alonso ^[1] ; Ayumi,Hashimoto ^[1] ; Prashanthi,Vonteddu ^[1] ; Reeti,Behera ^[1] ; Marlee A,Goins ^[2] ; Charles,Mulligan ^[2] ; Brian,Nam ^[2] ; Neil,Hockstein ^[2] ; Fred,Denstman ^[2] ; Shanti,Shakamuri ^[2] ; David W,Speicher ^[3] ; Ashani T,Weeraratna ^[1] ; Timothy,Chao ^[4] ; Robert H,Vonderheide ^[4] ; Lucia R,Languino ^[5] ; Peter,Ordentlich ^[6] ; Qin,Liu ^[1] ; Xiaowei,Xu ^[4] ; Albert,Lo ^[7] ; Ellen,Puré ^[7] ; Chunsheng,Zhang ^[8] ; Andrey,Loboda ^[8] ; Manuel A,Sepulveda ^[9] ; Linda A,Snyder ^[9] ; Dmitry I,Gabrilovich ^[10]

作者单位： Immunology, Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, PA 19104, USA. ^[1] Helen F. Graham Cancer Center at Christiana Care Health System, Wilmington, DE, USA. ^[2] Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, PA 19104, USA. ^[3] University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. ^[4] Sidney Kimmel Cancer Center, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA. ^[5] Syndax Pharmaceuticals, Inc., Waltham, MA 02451, USA. ^[6] University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19104, USA. ^[7] Department of Genetics and Pharmacogenomics, MRL, Merck & Co., Inc., Boston, MA 02115, USA. ^[8] Janssen R&D, Spring House, PA 19477, USA. ^[9] Immunology, Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, PA 19104, USA. Electronic address: dgabrilovich@wistar.org. ^[10]

关键词 CSF1R M-CSF PMN-MDSC fibroblasts granulocytes macrophages