Phosphorylation and Ubiquitination Regulate Protein Phosphatase 5 Activity and Its Prosurvival Role in Kidney Cancer.

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第一作者： Natela,Dushukyan

第一单位： Department of Urology, SUNY Upstate Medical University, 750 E. Adams St., Syracuse, NY 13210, USA; Upstate Cancer Center, SUNY Upstate Medical University, 750 E. Adams St., Syracuse, NY 13210, USA; Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, 750 E. Adams St., Syracuse, NY 13210, USA.

作者： Natela,Dushukyan ^[1] ; Diana M,Dunn ^[1] ; Rebecca A,Sager ^[1] ; Mark R,Woodford ^[2] ; David R,Loiselle ^[3] ; Michael,Daneshvar ^[2] ; Alexander J,Baker-Williams ^[1] ; John D,Chisholm ^[4] ; Andrew W,Truman ^[5] ; Cara K,Vaughan ^[6] ; Timothy A,Haystead ^[3] ; Gennady,Bratslavsky ^[2] ; Dimitra,Bourboulia ^[1] ; Mehdi,Mollapour ^[7]

作者单位： Department of Urology, SUNY Upstate Medical University, 750 E. Adams St., Syracuse, NY 13210, USA; Upstate Cancer Center, SUNY Upstate Medical University, 750 E. Adams St., Syracuse, NY 13210, USA; Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, 750 E. Adams St., Syracuse, NY 13210, USA. ^[1] Department of Urology, SUNY Upstate Medical University, 750 E. Adams St., Syracuse, NY 13210, USA; Upstate Cancer Center, SUNY Upstate Medical University, 750 E. Adams St., Syracuse, NY 13210, USA. ^[2] Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA. ^[3] Department of Chemistry, Syracuse University, 1-014 Center for Science and Technology, Syracuse, NY 13244, USA. ^[4] Department of Biological Sciences, University of North Carolina at Charlotte, Charlotte, NC 28223, USA. ^[5] Institute of Structural and Molecular Biology, University College London and Birkbeck College, Biological Sciences, Malet Street, London WC1E 7HX, UK. ^[6] Department of Urology, SUNY Upstate Medical University, 750 E. Adams St., Syracuse, NY 13210, USA; Upstate Cancer Center, SUNY Upstate Medical University, 750 E. Adams St., Syracuse, NY 13210, USA; Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, 750 E. Adams St., Syracuse, NY 13210, USA. Electronic address: mollapom@upstate.edu. ^[7]

关键词 PP5 VHL casein kinase-1 δ clear cell renal cell carcinoma co-chaperone heat shock protein 90 kidney cancer molecular chaperone serine/threonine phosphatase 5 von Hippel-Lindau protein