Telomere length of gallbladder epithelium is shortened in patients with congenital biliary dilatation: measurement by quantitative fluorescence in situ hybridization.

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作者： Yuto,Aoki ^[1] ; Junko,Aida ^[2] ; Youichi,Kawano ^[3] ; Ken-Ichi,Nakamura ^[3] ; Naotaka,Izumiyama-Shimomura ^[4] ; Naoshi,Ishikawa ^[3] ; Tomio,Arai ^[3] ; Yoshiharu,Nakamura ^[3] ; Nobuhiko,Taniai ^[5] ; Eiji,Uchida ^[6] ; Kaiyo,Takubo ^[6] ; Toshiyuki,Ishiwata ^[6]

作者单位： Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan. yutoaoki@nms.ac.jp. ^[1] Research Team for Geriatric Pathology and Department of Pathology, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan. yutoaoki@nms.ac.jp. ^[2] Research Team for Geriatric Pathology and Department of Pathology, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan. ^[3] Department of Surgery, Nippon Medical School Chiba Hokusoh Hospital, Chiba, Japan. ^[4] Department of Pathology, Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan. ^[5] Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan. ^[6] Research Team for Geriatric Pathology and Department of Pathology, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan. tishiwat@tmig.or.jp. ^[7]

关键词 Carcinogenesis Congenital biliary dilatation Pancreaticobiliary maljunction Q-FISH Telomere