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Harnessing BET Inhibitor Sensitivity Reveals AMIGO2 as a Melanoma Survival Gene.

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第一作者： Barbara,Fontanals-Cirera

第一单位： Department of Pathology and Interdisciplinary Melanoma Cooperative Group, New York University Langone Medical Center, New York, NY, USA.

作者： Barbara,Fontanals-Cirera ^[1] ; Dan,Hasson ^[2] ; Chiara,Vardabasso ^[2] ; Raffaella,Di Micco ^[1] ; Praveen,Agrawal ^[1] ; Asif,Chowdhury ^[2] ; Madeleine,Gantz ^[2] ; Ana,de Pablos-Aragoneses ^[1] ; Ari,Morgenstern ^[1] ; Pamela,Wu ^[3] ; Dan,Filipescu ^[2] ; David,Valle-Garcia ^[2] ; Farbod,Darvishian ^[1] ; Jae-Seok,Roe ^[4] ; Michael A,Davies ^[5] ; Christopher R,Vakoc ^[4] ; Eva,Hernando ^[6] ; Emily,Bernstein ^[7]

作者单位： Department of Pathology and Interdisciplinary Melanoma Cooperative Group, New York University Langone Medical Center, New York, NY, USA. ^[1] Departments of Oncological Sciences and Dermatology, 1470 Madison Avenue, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ^[2] Institute of Systems Genetics, New York University Langone Medical Center, New York, NY, USA. ^[3] Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY, USA. ^[4] Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. ^[5] Department of Pathology and Interdisciplinary Melanoma Cooperative Group, New York University Langone Medical Center, New York, NY, USA. Electronic address: eva.hernando-monge@nyumc.org. ^[6] Departments of Oncological Sciences and Dermatology, 1470 Madison Avenue, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: emily.bernstein@mssm.edu. ^[7]

关键词 AMIGO2 BET BET inhibition BRD2 BRD4 PTK7 enhancers melanoma