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Enhancing excitability of dopamine neurons promotes motivational behaviour through increased action initiation.

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第一作者： Linde,Boekhoudt

第一单位： Brain Center Rudolf Magnus, Department of Translational Neuroscience, University Medical Centre Utrecht, Universiteitsweg 100, 3585 CG Utrecht, The Netherlands.

作者： Linde,Boekhoudt ^[1] ; Ellen C,Wijbrans ^[1] ; Jodie H K,Man ^[1] ; Mieneke C M,Luijendijk ^[1] ; Johannes W,de Jong ^[2] ; Geoffrey,van der Plasse ^[1] ; Louk J M J,Vanderschuren ^[3] ; Roger A H,Adan ^[4]

作者单位： Brain Center Rudolf Magnus, Department of Translational Neuroscience, University Medical Centre Utrecht, Universiteitsweg 100, 3585 CG Utrecht, The Netherlands. ^[1] Brain Center Rudolf Magnus, Department of Translational Neuroscience, University Medical Centre Utrecht, Universiteitsweg 100, 3585 CG Utrecht, The Netherlands; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA. ^[2] Department of Animals in Science and Society, Division of Behavioural Neuroscience, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands. ^[3] Brain Center Rudolf Magnus, Department of Translational Neuroscience, University Medical Centre Utrecht, Universiteitsweg 100, 3585 CG Utrecht, The Netherlands. Electronic address: r.a.h.adan@umcutrecht.nl. ^[4]

关键词 DREADD Dopamine Motivation Substantia nigra TH-Cre rats Ventral tegmental area