The combined activation of K<sub>Ca</sub>3.1 and inhibition of K<sub>v</sub>11.1/hERG1 currents contribute to overcome Cisplatin resistance in colorectal cancer cells.

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作者： Serena,Pillozzi ^[1] ; Massimo,D'Amico ^[2] ; Gianluca,Bartoli ^[1] ; Luca,Gasparoli ^[1] ; Giulia,Petroni ^[1] ; Olivia,Crociani ^[1] ; Tiziano,Marzo ^[3] ; Angela,Guerriero ^[4] ; Luigi,Messori ^[1] ; Mirko,Severi ^[3] ; Roberto,Udisti ^[5] ; Heike,Wulff ^[5] ; K George,Chandy ^[6] ; Andrea,Becchetti ^[7] ; Annarosa,Arcangeli ^[8]

作者单位： Department of Experimental and Clinical Medicine, Section of Internal Medicine, University of Florence, Viale G.B. Morgagni 50, 50134 Firenze, Italy. ^[1] DIVAL Toscana Srl, Via Madonna del Piano 6, Sesto Fiorentino, 50119 Firenze, Italy. ^[2] Laboratory of Metals in Medicine (MetMed), Department of Chemistry, University of Florence, Via della Lastruccia 3, Sesto Fiorentino, 50019 Florence, Italy. ^[3] Department of Chemistry and Industrial Chemistry (DCCI), University of Pisa, Via Moruzzi 13, 56124 Pisa, Italy. ^[4] Department of Chemistry, University of Florence, Via della Lastruccia 3, Sesto Fiorentino, 50019 Florence, Italy. ^[5] Department of Pharmacology, 451 Health Sciences Drive, University of California, Davis, CA 95616, USA. ^[6] Laboratory of Molecular Physiology in the Infection and Immunity Theme, Lee Kong Chian School of Medicine, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore. ^[7] Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2, 20126 Milano, Italy. ^[8]