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Enrichment of colorectal cancer associations in functional regions: Insight for using epigenomics data in the analysis of whole genome sequence-imputed GWAS data.

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作者单位: Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America. [1] Joseph J. Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, United States of America. [2] Biomedical Informatics Program, Stanford University, Stanford, California, United States of America. [3] Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America. [4] Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America. [5] Service de Génétique Médicale, Centre Hospitalier Universitaire de Nantes, Nantes, France. [6] Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.;Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.;German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany. [7] Center for Public Health Genomics, Department of Public Health Sciences, University of Virginia School of Medicine, Charlottesville, Virginia, United States of America. [8] Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.;Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America. [9] Centre for Epidemiology and Biostatistics, Melbourne School of Population Health, The University of Melbourne, Melbourne, Victoria, Australia. [10] Division of Cancer Epidemiology C020, German Cancer Research Center (DKFZ), Heidelberg, Germany.;University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany. [11] Division of Medical Oncology, Stanford School of Medicine, Stanford, California, United States of America. [12] Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany. [13] Department of Molecular and Human Genetics, Baylor College of Medicine Center for Statistical Genetics, Houston, Texas, United States of America. [14] Ontario Institute for Cancer Research, MaRS Centre, South Tower, Toronto, Ontario, Canada. [15] Prevention and Cancer Control, Cancer Care Ontario, Toronto, Ontario, Canada. [16] Department of Medicine and Epidemiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America. [17] Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah, United States of America. [18] Department Genome Sciences, University of Washington, Seattle, Washington, United States of America. [19] University of Hawai'i Cancer Center, Honolulu, Hawai'i, United States of America. [20] Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.;Department of Epidemiology, University of Washington, Seattle, Washington, United States of America. [21] Division of Hematology, University of Ottawa, Ottawa, Ontario, Canada.;Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada. [22] Department of Genetics, Stanford University, Stanford, California, United States of America. [23] Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.;Department of Biostatistics, University of Washington, Seattle, Washington, United States of America. [24]
DOI 10.1371/journal.pone.0186518
PMID 29161273
发布时间 2024-09-22
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