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Social adversity and epigenetic aging: a multi-cohort study on socioeconomic differences in peripheral blood DNA methylation.

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作者单位: Italian Institute for Genomic Medicine (IIGM, former HuGeF), Via Nizza 52 -, 10126, Turin, Italy. [1] Department of Medical Sciences - University of Turin, C.So, Dogliotti, 14 - 10126, Italy. [2] Cancer Epidemiology & Intelligence Division, Cancer Council of Victoria, 615 St Kilda Road, Melbourne, Victoria, 3004, Australia. [3] Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville Victoria, 3010, Australia. [4] Department of Epidemiology and Public Health - University College London, 1-19 Torrington Place, London, WC1E 6BT, United Kingdom. [5] Institute of Evolutionary Biology and Environmental Studies, University of Zürich, Winterthurerstrasse 190, Zürich, Switzerland. [6] Institute of Biology, Medicinal Chemistry, and Biotechnology, National Hellenic Research Foundation, Leof. Vasileos Konstantinou 48, Athens, 116 35, Greece. [7] Fondazione IRCCS - Istituto Nazionale dei Tumori, Via Venezian 1, 20133, Milan, Italy. [8] Istituto per lo Studio e la Prevenzione Oncologica (ISPO Toscana), Via Cosimo Il Vecchio, 2, 50139, Florence, Italy. [9] Department of Clinical Medicine and Surgery, University of Naples Federico II, Corso Umberto I, 40, 80138, Naples, Italy. [10] Piedmont Reference Centre for Epidemiology and Cancer Prevention (CPO Piemonte), Via Santena 7, 10126, Turin, Italy. [11] Cancer Registry and Histopathology Department, 'Civic - M. P. Arezzo' Hospital, ASP Ragusa, Piazza Igea, 1, 97100, Ragusa, Italy. [12] MRC-PHE Centre for Environment and Health, Imperial College London, St. Mary's Campus Paddington, W2 1PG, London, United Kingdom. [13] Institute of Social and Preventive Medicine Lausanne University Hospital (CHUV), Rue du Bugnon 46, 1011, Lausanne, Switzerland. [14] Inserm U1018, Center for Research in Epidemiology and Population Health (CESP), Gustave Roussy Institute, 114 rue Edouard Vaillant, 94805, Villejuif Cedex, France. [15] Centre for Genomic and Experimental Medicine - University of Edinburgh, Crewe Road, EH4 2XU, Edinburgh, United Kingdom. [16] Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research (CNCR), Neuroscience Campus Amsterdam (NCA), VU University Amsterdam, De Boelelaan, 1085-1087 1081 HV, Amsterdam, The Netherlands. [17] Trinity College Dublin, Dublin, Ireland, UK. [18] Department of Clinical and Experimental Medicine, University of Pisa, Lungarno Antonio Pacinotti, 43, 56126, Pisa, Italy. [19] Italian Institute for Genomic Medicine (IIGM, former HuGeF), Via Nizza 52 -, 10126, Turin, Italy. p.vineis@imperial.ac.uk. [20] MRC-PHE Centre for Environment and Health, Imperial College London, St. Mary's Campus Paddington, W2 1PG, London, United Kingdom. p.vineis@imperial.ac.uk. [21]
DOI 10.1038/s41598-017-16391-5
PMID 29176660
发布时间 2022-03-30
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