首页> Journal of autoimmunity> Selective targeting of pro-inflammatory Th1 cells by microRNA-148a-specific antagomirs in vivo.

Selective targeting of pro-inflammatory Th1 cells by microRNA-148a-specific antagomirs in vivo.

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第一作者： Patrick,Maschmeyer

第一单位： Deutsches Rheuma-Forschungszentrum Berlin (DRFZ), Germany.

作者： Patrick,Maschmeyer ^[1] ; Georg,Petkau ^[1] ; Francesco,Siracusa ^[1] ; Jakob,Zimmermann ^[1] ; Franziska,Zügel ^[1] ; Anja Andrea,Kühl ^[2] ; Katrin,Lehmann ^[1] ; Sarah,Schimmelpfennig ^[1] ; Melanie,Weber ^[1] ; Claudia,Haftmann ^[1] ; René,Riedel ^[1] ; Markus,Bardua ^[1] ; Gitta Anne,Heinz ^[1] ; Cam Loan,Tran ^[1] ; Bimba Franziska,Hoyer ^[3] ; Falk,Hiepe ^[3] ; Sebastian,Herzog ^[4] ; Jürgen,Wittmann ^[5] ; Nikolaus,Rajewsky ^[6] ; Fritz Georg,Melchers ^[1] ; Hyun-Dong,Chang ^[1] ; Andreas,Radbruch ^[1] ; Mir-Farzin,Mashreghi ^[7]

作者单位： Deutsches Rheuma-Forschungszentrum Berlin (DRFZ), Germany. ^[1] Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin und Berlin Institute of Health, Campus Benjamin Franklin, Berlin, Germany. ^[2] Deutsches Rheuma-Forschungszentrum Berlin (DRFZ), Germany; Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin und Berlin Institute of Health, Campus Benjamin Franklin, Berlin, Germany. ^[3] Division of Developmental Immunology, BIOCENTER, Medical University Innsbruck, Innsbruck, Austria. ^[4] Division of Molecular Immunology, Department of Internal Medicine III, Nikolaus-Fiebiger-Center, University of Erlangen-Nürnberg, Erlangen, Germany. ^[5] Berlin Institute for Medical Systems Biology, Berlin, Germany. ^[6] Deutsches Rheuma-Forschungszentrum Berlin (DRFZ), Germany. Electronic address: mashreghi@drfz.de. ^[7]

关键词 Antagomirs Chronic inflammation Inflammatory bowel disease Oligonucleotide therapy Pre-clinical study Pro-inflammatory Th1 cells miRNA-148a