Triptolide suppresses paraquat induced idiopathic pulmonary fibrosis by inhibiting TGFB1-dependent epithelial mesenchymal transition.

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作者： Hong,Chen ^[1] ; Qun,Chen ^[2] ; Chun-Ming,Jiang ^[3] ; Guang-Yue,Shi ^[4] ; Bo-Wen,Sui ^[5] ; Wei,Zhang ^[5] ; Li-Zhen,Yang ^[5] ; Zhu-Ying,Li ^[5] ; Li,Liu ^[5] ; Yu-Ming,Su ^[5] ; Wen-Cheng,Zhao ^[3] ; Hong-Qiang,Sun ^[3] ; Zhen-Zi,Li ^[6] ; Zhou,Fu ^[7]

作者单位： Department of Respiratory Medicine, Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, China; China International Science and Technology Cooperation base of Child development and Critical Disorders, China; Chongqing Engineering Research Center of Stem Cell Therapy, China; Department of Pediatrics, First Affiliated Hospital, Heilongjiang University Of Chinese Medicine, China. ^[1] Department of Laboratory, The People's Hospital of Acheng District, Harbin, China. ^[2] The First Affiliated Hospital of Harbin Medical University, China. ^[3] Harbin Medical University Cancer Hospital, China. ^[4] First Affiliated Hospital, Heilongjiang University Of Chinese Medicine, China. ^[5] Harbin Medical University, China. ^[6] Department of Respiratory Medicine, Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, China; China International Science and Technology Cooperation base of Child development and Critical Disorders, China; Chongqing Engineering Research Center of Stem Cell Therapy, China. Electronic address: fu-zhou79@aliyun.com. ^[7]

关键词 EMT Idiopathic pulmonary fibrosis Paraquat TGFB1 Triptolide