When and how should multiple imputation be used for handling missing data in randomised clinical trials - a practical guide with flowcharts.

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作者： Janus Christian,Jakobsen ^[1] ; Christian,Gluud ^[2] ; Jørn,Wetterslev ^[3] ; Per,Winkel ^[3]

作者单位： The Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. jcj@ctu.dk. ^[1] Department of Cardiology, Holbæk Hospital, Holbæk, Denmark. jcj@ctu.dk. ^[2] The Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. ^[3]

关键词 Missing data Multiple imputation Randomised clinical trials

主题词数据说明, 统计(Data Interpretation, Statistical);人类(Humans);模型, 统计学(Models, Statistical);随机对照试验(主题)(Randomized Controlled Trials as Topic)

DOI 10.1186/s12874-017-0442-1

PMID 29207961

发布时间 2022-04-08

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