Frequency-Dependent Multi-Well Cardiotoxicity Screening Enabled by Optogenetic Stimulation.

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第一作者： Susanne,Rehnelt

第一单位： Institute of Physiology I, Medical Faculty, University of Bonn, 53127 Bonn, Germany. s4surehn@uni-bonn.de.

作者： Susanne,Rehnelt ^[1] ; Daniela,Malan ^[2] ; Krisztina,Juhasz ^[3] ; Benjamin,Wolters ^[4] ; Leo,Doerr ^[5] ; Matthias,Beckler ^[6] ; Ralf,Kettenhofen ^[7] ; Heribert,Bohlen ^[8] ; Tobias,Bruegmann ^[9] ; Philipp,Sasse ^[10]

作者单位： Institute of Physiology I, Medical Faculty, University of Bonn, 53127 Bonn, Germany. s4surehn@uni-bonn.de. ^[1] Institute of Physiology I, Medical Faculty, University of Bonn, 53127 Bonn, Germany. dmalan@uni-bonn.de. ^[2] Nanion Technologies GmbH, 80636 Munich, Germany. krisztina.juhasz@nanion.de. ^[3] Present address: Institute for Nanoelectronics, Department of Electrical Engineering and Information Technology, Technische Universität München, 80339 Munich, Germany. krisztina.juhasz@nanion.de. ^[4] Part of the Ncardia Group, Axiogenesis AG, 50829 Cologne, Germany. benjamin.wolters@ncardia.com. ^[5] Nanion Technologies GmbH, 80636 Munich, Germany. leo.doerr@nanion.de. ^[6] Nanion Technologies GmbH, 80636 Munich, Germany. matthias.beckler@nanion.de. ^[7] Part of the Ncardia Group, Axiogenesis AG, 50829 Cologne, Germany. ralf.kettenhofen@ncardia.com. ^[8] Part of the Ncardia Group, Axiogenesis AG, 50829 Cologne, Germany. heribert.bohlen@ncardia.com. ^[9] Institute of Physiology I, Medical Faculty, University of Bonn, 53127 Bonn, Germany. tbruegmann@uni-bonn.de. ^[10] Research Training Group 1873, University of Bonn, 53127 Bonn, Germany. tbruegmann@uni-bonn.de. ^[11] Institute of Physiology I, Medical Faculty, University of Bonn, 53127 Bonn, Germany. philipp.sasse@uni-bonn.de. ^[12]

关键词 cardiomyocytes cardiotoxicity screening field potential heart rate induced pluripotent stem cells long QT syndrome optogenetics