Chromosome structures: reduction of certain problems with unequal gene content and gene paralogs to integer linear programming.

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作者： Vassily,Lyubetsky ^[1] ; Roman,Gershgorin ^[2] ; Konstantin,Gorbunov ^[1]

作者单位： Institute for Information Transmission Problems of the Russian Academy of Sciences (Kharkevich Institute), Bolshoy Karetny per. 19, build.1, Moscow, 127051, Russia. ^[1] Faculty of Mechanics and Mathematics, Lomonosov Moscow State University, Leninskiye Gory 1, Main Building, Moscow, 119991, Russia. ^[2] Institute for Information Transmission Problems of the Russian Academy of Sciences (Kharkevich Institute), Bolshoy Karetny per. 19, build.1, Moscow, 127051, Russia. gorbunov@iitp.ru. ^[3]

关键词 Ancestral genome Chromosomal rearrangement Chromosome structure Efficient algorithms Evolution along the tree Integer linear programming Parsimony principle Reconstruction of ancestral genomes Transformation of chromosome structures

主题词生物进化(Biological Evolution);染色体结构(Chromosome Structures);计算生物学(Computational Biology);基因组(Genome);模型, 遗传学(Models, Genetic);种系发生(Phylogeny);规划, 线性(Programming, Linear)

DOI 10.1186/s12859-017-1944-x

PMID 29212445

发布时间 2018-12-02

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