Atypical dopamine transporter inhibitors attenuate compulsive-like methamphetamine self-administration in rats.

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作者： Brendan J,Tunstall ^[1] ; Chelsea P,Ho ^[1] ; Jianjing,Cao ^[2] ; Janaína C M,Vendruscolo ^[1] ; Brooke E,Schmeichel ^[1] ; Rachel D,Slack ^[2] ; Gianluigi,Tanda ^[2] ; Alexandra J,Gadiano ^[3] ; Rana,Rais ^[4] ; Barbara S,Slusher ^[4] ; George F,Koob ^[1] ; Amy H,Newman ^[5] ; Leandro F,Vendruscolo ^[6]

作者单位： Neurobiology of Addiction Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA. ^[1] Molecular Targets and Medications Discovery Program, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA. ^[2] Molecular Targets and Medications Discovery Program, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA; Department of Neurology, Johns Hopkins Drug Discovery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. ^[3] Department of Neurology, Johns Hopkins Drug Discovery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. ^[4] Molecular Targets and Medications Discovery Program, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA. Electronic address: anewman@intra.nida.nih.gov. ^[5] Neurobiology of Addiction Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA. Electronic address: leandro.vendruscolo@nih.gov. ^[6]

关键词 Addiction Dopamine transporter (DAT)Drug dependence Methamphetamine Operant intravenous self-administration